
Hyperbaric oxygen at Breathe
Oxygen behaves differently
under pressure.
Under pressure, more oxygen can dissolve in blood plasma and move beyond normal circulation limits. That simple change is where hyperbaric oxygen gets interesting. Here’s what happens next, and what the research says about it.
Book nowHyperbaric packages start at £199, and our membership starts at £349 a month.
See pricingWhat is it? And what does it do for me?
Scroll through the animation to understand hyperbaric oxygen therapy.
One breath, and oxygen crosses into the blood
It has about a quarter of a second in the lungs to do it. Follow it to a single red cell.
Four seats. That is all one red cell has.
Each haemoglobin group takes one oxygen molecule. Four groups, four seats, and the first one makes the next easier to fill.
Breathing ordinary air, those seats are about 97 per cent taken
Which is the part everyone skips. You cannot meaningfully load more oxygen onto a red cell, because there is almost no room left on it.
The cell releases where the body asks
Warmer, harder-working tissue pulls the oxygen off the haemoglobin, and the cell travels on empty, ready to be filled again.
So the extra oxygen goes into the river instead
At pressure, oxygen dissolves directly into the plasma, the fluid your cells are carried in. It needs no seat and no red cell, and it reaches places red cells cannot.
The research
There’s a reason we’re this interested.
Hyperbaric oxygen has a long medical history, including established uses such as treating gas embolism. Research also reaches into conditions such as fibromyalgia, where clinical trials have reported encouraging findings.
Understanding who benefited and how they were treated is part of understanding the result. We bring that detail together in our Library, with plain-English summaries and links to the original studies, organised by condition or goal so you can find what matters to you.
Dissolved oxygen at 1.5 ATA
Strong
This is physics rather than medicine. Raising the pressure and the oxygen fraction raises the oxygen physically dissolved in plasma. It is measured routinely, in arterial blood gases and by transcutaneous oximetry, and nobody disputes it. Research at lower pressures is a younger field than the hospital work: seventeen controlled trials in the 1.25 to 1.75 ATA band, three of them double-blind trials at 1.5 ATA whose treated groups separated from a dummy session.
Worth knowing: a mechanism sits one rung below proof, and the gap between those rungs is wider than it looks.
Read the studies in fullDecompression illness
Strong
Hyperbaric oxygen is the definitive treatment for decompression illness, and it is the clearest case in the whole field. It is also hospital emergency medicine, delivered at around 2.8 ATA under a hyperbaric physician. It is here because it is the reason the biology is taken seriously at all.
Worth knowing: Breathe does not treat decompression illness. Anyone who needs it belongs in a hospital unit immediately.
Read the studies in fullThe recognised hospital indications
Strong
The indications manual of the Undersea and Hyperbaric Medical Society recognises fourteen indications, and the society's current online list adds two more. Every one of them is an acute or serious medical condition managed in a hospital hyperbaric unit, usually as an emergency, usually at 2.0 to 3.0 ATA. We do not treat any of them and we do not accept referrals for any of them.
Worth knowing: approval is specific to each indication. It is approved for some things, so it must be fine for mine is a misconception, and a common one.
Read the studies in fullProblem wounds and diabetic foot ulcers
Moderate
A Cochrane review pooled twelve randomised trials and 577 participants and reported improved healing at six weeks when hyperbaric oxygen was added to specialist wound care in a hospital chamber. The benefit was not evident at longer follow-up, and there was no statistically significant difference in major amputation. When tissue oxygen was measured beside chronic ulcers in 130 people, 1.4 ATA reached 161 mmHg against 333 mmHg at 2.0 ATA, and the authors concluded the lower pressure does not reach the levels associated with healing.
Worth knowing: approved in a hospital, at hospital pressures, alongside a podiatry team. A member with a diabetic foot ulcer belongs under specialist wound care.
Read the studies in fullRadiation tissue injury
Moderate
A 2023 Cochrane review of eighteen trials and 1,071 participants reported a pain reduction of about 10.7 points at twelve months in osteoradionecrosis at moderate certainty, and reduced wound breakdown after surgery in irradiated head and neck tissue at low certainty. Two prevention trials were negative: 144 patients given 30 sessions at 2.4 ATA before dental surgery saw osteoradionecrosis in 6.4 per cent against 5.7 per cent of controls, and a trial in 189 women after breast radiotherapy missed its primary pain endpoint.
Worth knowing: a past course of radiotherapy is not a barrier to a session with us. A radiation dose within the last 24 hours is, and that is a timing rule rather than a lifetime bar.
Read the studies in fullLong COVID
Early
One well-conducted sham-controlled trial of 73 people, given 40 daily ninety-minute sessions at 2.0 ATA, reported a significant improvement in global cognition against sham, with secondary gains in energy, sleep, psychiatric symptoms and pain interference. Against that, a sham-controlled trial of 80 people given 10 sessions at 2.4 ATA missed both primary endpoints, and a registry of 232 patients had no control group. Course length is the most likely explanation for the difference, but that is a hypothesis rather than a finding.
Worth knowing: these trials ran at 2.0 ATA and above, in hospital chambers. They are here as context for the field.
Read the studies in fullFibromyalgia
Early
A crossover trial that analysed 48 women, given 40 sessions of 90 minutes at 2.0 ATA, reported large improvements in the Fibromyalgia Impact Questionnaire and in tender point counts; its authors listed a single site, no blinding and self-reported outcomes as limitations. A 2023 meta-analysis of four trials and 163 participants reported improvement in that questionnaire but no significant difference in pain on a visual-analogue scale, and significantly more side effects in the hyperbaric groups, most of them middle ear barotrauma.
Worth knowing: these trials ran at 2.0 ATA and above. The side-effect finding is worth reading before you book anything.
Read the studies in fullSleep and feeling refreshed
Early
Members often tell us they sleep well the night after a session. That is what they report, and it is not something the session is shown to do. In the research, better sleep appears only as a secondary finding: in two small 1.5 ATA trials in people with persistent symptoms after a head injury, and in a long COVID trial of 40 sessions at 2.0 ATA. It has not been confirmed as a primary endpoint.
Worth knowing: we will keep telling you what members say. We will not turn it into a statement about what the chamber does.
Read the studies in full













