Photobiomodulation therapy for the improvement of muscular performance and reduction of muscular fatigue associated with exercise in healthy people: a systematic review and meta-analysis
Read the paperWhat they asked
By the mid-2010s there were dozens of small trials shining light on muscle before or after exercise, with mixed results and no agreement on how much energy to use or when to apply it. This international group asked whether, pooled together, the trials show improved muscular performance and reduced fatigue in healthy people, and whether a dose window can be identified from the pattern of positive and negative results.
Who took part
The review covered randomised trials in healthy volunteers rather than people with an injury or illness, which is important because light appears to do more in stressed tissue than in tissue that is already working well. Participants were typically young and active, often recreational athletes, and the exercise tasks ranged from repeated knee extensions to cycling and running protocols designed to induce fatigue.
What they did
The authors searched the literature, pooled outcomes such as repetitions to fatigue, time to exhaustion, peak torque and blood markers of muscle damage including creatine kinase and lactate, and grouped trials by wavelength, energy per site and whether the light was applied before or after exercise. Each trial compared active light against a placebo device.
What they found
The review reported that near-infrared light applied to muscle before exercise increased repetitions to fatigue and reduced markers such as creatine kinase compared with placebo. The pattern of results suggested a dose window of roughly 20 to 60 joules per muscle site, with less effect above and below it. Application before exercise generally looked better supported than application afterwards.
What it means
This is the basis for the claim that light may support muscle performance, and it is a real signal. The catch for members is the delivery again: 20 to 60 joules concentrated on one muscle site, from a cluster probe held against the leg, is a different proposition from a few minutes standing in front of a panel. Nothing here describes a whole-body session.
Limits
Most of the pooled trials were small and conducted in laboratory conditions with tasks chosen to be sensitive to change rather than to resemble training. Healthy young volunteers have the least room to improve, which cuts both ways. Publication bias is a real risk in a field of small positive studies. The dose window was inferred across trials rather than tested directly, and outcomes such as repetitions to fatigue do not necessarily translate into better training over a season.







